Herpes Simplex Virus Glycoprotein C Regulates Low-pH Entry
ABSTRACT Herpes simplex viruses (HSVs) cause significant morbidity and mortality in humans worldwide.Herpesviruses mediate entry by a multicomponent virus-encoded machinery.Herpesviruses enter cells by Toddler Pillow endosomal low-pH and pH-neutral mechanisms in a cell-specific manner.HSV mediates cell entry via the envelope glycoproteins gB and gD